To keep the "..from hell" motiff going, this CC is about, well, girlfriends from hell. Of course, I realize that this could apply to every girlfriend you've ever had (about 90% for myself).
Make a comic about a girlfriend you've had in the past, or someone you're currently seeing, or even just a bad date you've had, or maybe, someone you've married. OR make a comic about a celebrity that you could imagine would be a girlfriend from hell.
No rules, just fun!