There's long been a problem with disappearing commas in profiles; commas simply aren't added when you press submit. While we wait for the official hotfix, you can get around the problem with HTML code. Just use , in place of commas -- that's ampersand, number sign, four, four, semicolon. This will add a comma in its place which doesn't get removed when you submit the updated profile.
Keep in mind, though, that if you go to edit your profile again, the edit tab will display regular commas, not the HTML code, which means if you just press update, the commas will disappear. You have to add , every time you update anything in the profile, so I recommend just copying your profile to a .txt file on your computer for easy copy-pasting action later.
While on the topic of HTML code, you can use ' ' if you need to add consecutive non-breaking spaces in text -- that's ampersand, n, b, s, p, semicolon. This is a great trick for adding multiple consecutive spaces after another, or for forcing words onto the next line in speech bubbles, i.e.
In other words, HTML Code is awesome, and if you need more, here's a reference chart:
http://www.ascii.cl/htmlcodes.htm
I originally posted this in the original thread reporting this bug at http://www.stripcreator.com/forums/showthread.php?postnum=267301 , but I'll re-post it here to make sure people know about it. Hope you don't mind.
Off-topic: Yay, I'm a donor.