What, are you joking? Think of the possibilites...
Strong Bad: Oh, the cheat, you have two butts!
The Cheat: Maw ma-maw meet maddah maw!
Homestar: Thanks, for the boots!
We could also have Strong Bad reading emails by using him and the pc prop. I went to a homestarrunner board for nearly one year, and everyone wanted to make their own emails. Just dream, my friends... dream...
Also, I don't think this will happen, because the Brothers Chaps are somewhat uptight about that sort of thing.