The Disco Biscuits (preferrably a live album) are an up-and-coming "jam" band (though "jam" doesn't mean much anymore) that is influencing the way electronic music and rock are merging in a concert setting. I'd also recommend Keller Williams, a great 10-string guitarist that plays with loop machines and can just play a mean, percussive, fast, kottke-esque guitar while singing pretty country/bluegrass-ish melodies with some good hooks.
And of course: Medeski, Martin, and Wood. They're pretty famous in the jazz world, but I think they appeal to anyone who likes a good groove.
The Disco Biscuits
Keller Williams
MMW
Just the first three pretty unknown-yet-amazing bands/mans that came into my head.
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Sex Piano.