I've been getting this error message frequently in the last week. It happens both when I click on comics and forum threads. Refreshing the page usually resolves it.
Brad's Magical Comic Making Machine wrote:
Internal Server Error
The server encountered an internal error or misconfiguration and was unable to complete your request.
Please contact the server administrator, firstname.lastname@example.org and inform them of the time the error occurred, and anything you might have done that may have caused the error.
More information about this error may be available in the server error log.
Additionally, a 404 Not Found error was encountered while trying to use an ErrorDocument to handle the request.
FWIW, I'm on a mac using Chrome.